Antiox NAD+ Serum

There comes a moment when skin stops responding the way it used to. Its glow fades, recovery becomes slower and the signs of time settle in without warning. The answer isn't just about hydrating the surface, but about giving back energy to the cells that sustain skin vitality. This is SEGLE's ultimate antioxidant defence: a high-precision biotechnological formula that brings together nine antioxidants to protect, repair and extend your skin's longevity.

A new-generation antioxidant defence

Designed for those who want to take anti-ageing care one step further, this serum concentrates nine advanced-technology antioxidants that work at different levels of the skin. Alongside classic active ingredients such as ferulic acid, vitamin C, vitamin E and niacinamide, it incorporates cutting-edge biotechnological molecules such as astaxanthin and EUK-134™, capable of continuously neutralising oxidative damage.

Its distinctive peach tone isn't a cosmetic additive: it occurs naturally from two of its active ingredients, astaxanthin and coenzyme Q10, visible proof of a formula rich in pure active ingredients.

Benefits you'll notice on your skin

• Superior antioxidant protection: defends the skin against oxidative damage caused by sun, pollution and stress.
• Cellular energy and longevity: boosts NAD⁺ levels and sirtuin activity, reactivating the skin's vitality from within.
• Reinforced skin barrier: with ceramides, niacinamide and hyaluronic acid for more hydrated, elastic and smooth skin.
• Radiance and even tone: lightens dark spots and visibly improves texture from the first weeks.
• Greater firmness: smooths expression lines and restores skin's smoothness.

Its efficacy has been clinically tested on volunteers according to European regulations, with results of +58 % in hydration, +25 % in radiance and +45 % in DNA protection.

The axis of cellular energy: why NAD⁺ matters

Skin doesn't age solely due to external damage. It ages because, over time, its cells lose the ability to defend and regenerate themselves. Behind that loss is an essential molecule: NAD⁺, a coenzyme the body itself produces that regulates vital cell functions.

• Produces energy: it's essential for mitochondrial function. Without enough NAD⁺, the cell works more slowly and recovers less effectively.
• Repairs DNA: every time the skin is damaged, it activates repair mechanisms that consume NAD⁺. If it runs low, damage accumulates.
• Activates sirtuins: proteins that regulate cellular ageing, protect DNA integrity and modulate inflammation.

From the age of 40, NAD⁺ levels can drop by up to 50 %. The result is skin that repairs less effectively, loses radiance and takes longer to recover. Caring for NAD⁺ means caring for the skin from within: this is what SEGLE calls skin longevity. That's why this formula includes an NAD⁺ booster complex that, together with niacinamide, stimulates its synthesis inside the cell, working where no conventional antioxidant can reach.

The active ingredients that transform your skin

Vitamin C Complex at 10 % (three forms)

A multi-form formulation that guarantees stability, penetration and efficacy at every level of the skin.

• Tetrahexyldecyl Ascorbate: fat-soluble, with maximum dermal penetration.
• Ascorbyl Glucoside: stable, with uniform and sustained action.
• 3-O-Ethyl Ascorbic Acid: with high bioavailability.

Ferulic acid

A plant-derived antioxidant found in seeds and leaves of plants such as rice or wheat. It neutralises free radicals, protects against UV and infrared radiation and enhances the effect of vitamins C and E, providing firmness and radiance. Its ability to stabilise these active ingredients has made it a key reinforcement in high-end antioxidant formulas.

Niacinamide

Known as vitamin B3, it's a multi-action active ingredient that is exceptionally well tolerated. It reduces dark spots and evens out tone, calms redness and irritation, regulates excess oil and strengthens the skin's natural barrier. It also stimulates the production of ceramides, the essential lipids that keep skin strong and healthy.

Coenzyme Q10

A natural molecule present in our cells and key to energy production. It neutralises free radicals, improves the energy production of skin cells, reduces wrinkles and restores radiance to the face. Its levels decline with age, hence the value of applying it topically to mature skin.

Vitamin E

A fundamental antioxidant that protects skin against environmental aggressors and helps keep it smooth and hydrated. It reinforces the skin barrier, calms irritation, prevents the appearance of dark spots and enhances the action of vitamin C. Naturally present in sebum, it acts as the first line of antioxidant defence on the skin's surface.

Astaxanthin

A carotenoid obtained from the alga Haematococcus pluvialis, with antioxidant power up to 6,000 times greater than vitamin C. It protects against oxidative stress and sun damage, reduces inflammation, prevents wrinkles and loss of elasticity, and provides radiance. It's the same pigment that gives salmon and krill their colour, and one of the most powerful natural antioxidants known.

EUK-134™

A biomimetic antioxidant that mimics the action of superoxide dismutase (SOD) and catalase, the two most important endogenous antioxidant enzymes in our mitochondria. Unlike other antioxidants, it regenerates itself and neutralises free radicals continuously without depleting, offering up to 45 % of protection against UV damage to DNA and a 46 % reduction in erythema.

NAD⁺ Booster Complex

A marine biotechnology complex obtained from the microalga Chlorella vulgaris. It reactivates cellular energy by increasing NAD⁺, helps repair DNA damaged by oxidative stress and the passage of time, and strengthens skin's resistance to ageing, restoring firmness, evenness and radiance to fatigued skin.

RejuveNAD™

A biotechnological extract from sunflower sprouts (Helianthus Annuus Sprout Extract) that activates the NAMPT enzyme, the rate-limiting step in NAD⁺ synthesis, naturally and sustainably stimulating its endogenous production. In clinical study, skin appears 8.2 years younger after 42 days of use.

Biomimetic ceramide complex

Accurately reproduces the structure of the stratum corneum, with NP, AP and EOP ceramides, phytosphingosine, cholesterol and glycosphingolipids in physiological proportions. Clinical studies show +57.3 % hydration after five days, a 81 % reduction in itching and a 92 % increase in hyaluronic acid in vitro at 24 hours.

Who it's for

Suitable for all skin types, it's especially recommended for mature skin or skin regularly exposed to aggressive environmental factors such as sun, pollution or stress. Not recommended for very sensitive or reactive skin. This is your serum if you're looking for a superior level of antioxidant protection, if your skin looks dull or shows signs of premature ageing, and if you want to improve hydration, firmness and cellular longevity from within.

How to use

• Apply 2 or 3 doses to clean, dry skin on the face, neck and décolletage, morning and/or evening.
• In the morning, always follow with sunscreen.
• For a complete, maximum-power anti-ageing routine, combine it with the Collagen NAD⁺ serum or cream.

Ingredients (INCI)

AQUA, ASCORBYL GLUCOSIDE, PROPYLENE GLYCOL, 3-O-ETHYL ASCORBIC ACID, DIMETHICONE, NIACINAMIDE, TETRAHEXYLDECYL ASCORBATE, TOCOPHEROL, ASTAXANTHIN, FERULIC ACID, UBIQUINONE, NICOTINAMIDE ADENINE DINUCLEOTIDE, SPHINGOMONAS FERMENT EXTRACT, CHLORELLA VULGARIS EXTRACT, HELIANTHUS ANNUUS SPROUT EXTRACT, SODIUM HYALURONATE, CERAMIDE AP, CERAMIDE NP, CHOLESTEROL, SQUALENE, GLYCERIN, HYDROGENATED TETRAACETYLPHYTOSPHINGOSINE, GLYCO-SPHINGOLIPIDS, LECITHIN, CETEARYL ALCOHOL, GLYCERYL STEARATE, 1.2-HEXANEDIOL, STEARIC ACID, XANTHAN GUM, SUCCINOGLYCAN, SODIUM HYDROXIDE, GLYCINE SOJA OIL, PROPANEDIOL, CAPRYLYL GLYCOL, CAPRYLIC/CAPRIC TRIGLYCERIDE, PENTYLENE GLYCOL, MICA, SODIUM PHYTATE, TOCOPHERYL ACETATE, MALTODEXTRIN, BETA-SITOSTEROL, TITANIUM DIOXIDE, PHENYLPROPANOL, PARFUM, HEXYL CINNAMAL, LINALOOL, ETHYLBISIMINO-METHYLGUAIACOL MANGANESE CHLORIDE, CITRUS AURANTIUM PEEL OIL, LIMONENE, PINENE, CITRAL.