Pure Retinol Serum

SEGLE Biotech’s Pure Retinol Serum is a high-performance global anti-aging night treatment that combines 0.3% pure retinol with marine retinal biotech from blue biotechnology to transform the skin while you sleep. A sophisticated, powerful yet carefully balanced formula with niacinamide, centella asiatica, licorice, and bisabolol, designed to smooth wrinkles, improve firmness, even tone, and refine texture with maximum efficacy and optimized tolerability.

Who is this serum for?

This night serum is designed for those seeking a true skin-renewal treatment, with visible results across all signs of aging:

• Skin with expression lines and more pronounced wrinkles, loss of firmness and elasticity.
• Dull skin, with dark spots or uneven tone that needs uniformity and radiance.
• Combination or oily skin with enlarged pores, uneven texture, and a tendency toward excess sebum.
• Skin concerned about sensitivity or redness that doesn’t want to give up a powerful retinoid, but is looking for a balanced, soothing formula.

Not suitable for pregnancy or breastfeeding.

Visible skin benefits

• Gradually smooths expression lines and deeper lines by stimulating collagen and elastin.
• Improves firmness and elasticity by redensifying the skin and reinforcing its support structure.
• Even tone and helps reduce dark spots, signs of photoaging, and small imperfections.
• Adds radiance and refinement: skin feels smoother, finer, more even, and smoother to the touch.
• Regulates sebum production and improves the appearance of pores—ideal for combination skin or skin with an acne-prone tendency.
• Strategically soothing formula thanks to niacinamide, centella asiatica, licorice, and bisabolol, which help minimize irritation and redness.
• Lightweight serum texture with rapid absorption, perfect for integrating into sophisticated routines without a greasy feel.

Advanced anti-aging technology: synergy between pure retinol and marine retinal

The heart of Pure Retinol Serum lies in the combination of 0.3% pure retinol with 3-hydroxy-apo-15-carotenal (marine retinal) encapsulated from the microalga Chlorella vulgaris. This dual action pathway accelerates cellular renewal, improves dermal architecture, and works on wrinkles, sagging, dark spots, and texture, with an efficacy characteristic of next-generation retinoids.

Key actives and skin action

0.3% pure retinol – the “gold standard” for anti-aging

Retinol is one of the most studied and recognized ingredients in cosmetic dermatology. Derived from vitamin A, it is considered the reference standard in anti-aging treatments for its ability to transform skin on multiple levels.

• Stimulates the synthesis of collagen and elastin, helping smooth wrinkles and expression lines.
• Accelerates epidermal renewal, improving texture and refining the skin’s surface relief.
• Helps unify tone and reduce dark spots of sun or hormonal origin.
• Regulates excess oil and improves the appearance of pores, especially in combination skin and skin with an acne-prone tendency.

Retinol works at the cellular level by modulating gene expression, which explains its deeply transformative character in terms of skin quality.

Marine Retinal – Blue biotechnology from the microalga Chlorella vulgaris

The marine retinal used by SEGLE is obtained from a specific carotenoid of the microalga Chlorella vulgaris, cultivated under conditions of extreme salinity and high UV radiation on the island of Formentera. To protect itself from the environment, the microalga synthesizes this carotenoid which, through blue biotechnology, is transformed into a highly effective cosmetic active.

• Acts through the same mechanism as pure retinal, but with greater tolerance at the epidermal level.
• Promotes cell renewal and improves the overall skin texture.
• Stimulates collagen and elastin, helping reduce wrinkles and sagging.
• Unifies the tone and adds luminosity, delivering a more even and radiant appearance.
• Provides protection against oxidative and environmental stress.

Its molecular structure, identical to that of retinal, and its sustainable method of production make it a new-generation marine retinoid—powerful and respectful of the skin.

5% Niacinamide – Balance, soothe, and brighten

Niacinamide (vitamin B3) is a high-tolerance, multi-action active that complements and balances the potency of retinoids.

• Helps reduce dark spots and unevenness of tone, enhancing facial brightness.
• Calms redness and irritation, improving comfort in reactive skin.
• Regulates excess sebum and refines the appearance of pores.
• Strengthens the skin barrier by stimulating ceramide production, improving hydration and elasticity.
• Provides antioxidant protection against the free radicals involved in premature aging.

Centella asiatica extract – Repair and firmness

Centella asiatica is an iconic plant in skincare phytotherapy due to its regenerative and soothing properties.

• Stimulates collagen synthesis, promoting firmer and more elastic skin.
• Accelerates skin repair and recovery processes.
• Calms redness and reduces the sensation of irritation.
• Adds an antioxidant boost to help protect the skin from environmental aggressors.

Licorice extract (glycyrrhetinic acid) – Evenness and comfort

Licorice root extract, rich in glabridin, is a natural active highly valued in depigmenting and soothing treatments.

• Lightens dark spots and contributes to a more even skin tone.
• Calms the skin and helps reduce redness and inflammation.
• Offers protection against oxidative damage from external sources.
• Ideal as support for sensitive skin or skin prone to irritation.

Bisabolol – Deep calming and protection

Bisabolol is the primary soothing active in chamomile and one of the most appreciated molecules for caring for sensitive skin or skin exposed to intensive treatments.

• Reduces irritation and redness, providing an immediate calming sensation.
• Promotes repair of the skin barrier, which is key when using retinoids.
• Provides additional antioxidant action, helping prevent premature aging.

Recommended usage routine

Night application

• Always use it at night, on clean and completely dry skin.
• Apply 3 to 4 drops to the face (avoiding the direct eye contour), the neck, and, if desired, the décolletage.
• Spread with gentle touches or light presses until fully absorbed, without rubbing excessively.

Progressive introduction

• If it’s your first time using retinol, start with 2 nights per week during the first two weeks.
• From the third week onward, increase to alternate nights based on tolerance.
• Finally, you can use it every night if your skin tolerates it without signs of irritation.

Recommended synergies

• During the first weeks, to minimize possible discomfort, apply 15–20 minutes after a serum or moisturizing and repairing cream such as Skin Factor or Blue Balance.
• If your skin needs more nourishment, combine the serum with the Crema Pure Retinol, applied after a few minutes.
• In the morning, it is essential to finish the routine with a broad-spectrum sunscreen to protect the renewed skin.

Complete ingredient list (INCI)

AQUA (WATER), PROPANEDIOL, GLYCERIN, CETEARYL ETHYLHEXANOATE, RETINOL, 3-HYDROXY-APO-15-CAROTENAL, NIACINAMIDE, GLYCYRRHIZA GLABRA (LICORICE) ROOT EXTRACT, CENTELLA ASIATICA EXTRACT, BISABOLOL, HYDROGENATED LECITHIN, CARBOMER, SODIUM HYDROXIDE, 1,2-HEXANEDIOL, CAPRYLYL GLYCOL, ETHYLHEXYLGLYCERIN, PHENOXYETHANOL, PARFUM (FRAGRANCE).

The Pure Retinol Serum embodies the union between science, marine biotechnology, and luxurious cosmetic sensitivity: a precise and demanding night treatment, designed for those who want visibly smoother, more even, firmer, and radiant-looking skin as the weeks go by.