Inhibit High Definition Serum

The maximum cosmetic precision for your expression lines

There comes a moment when expression lines stop being subtle and begin to shape your gesture, your gaze, and your facial contour. That’s exactly where Inhibit High Definition Serum comes into play, the master formula of Natura Bissé inspired by medical-aesthetic filler treatments. An ultra-concentrated serum that helps relax lines, fill wrinkles, tighten contours, and visibly rejuvenate the skin, without giving up the pleasure of a high-cosmetics ritual.

Intensive correction inspired by aesthetic medicine

After a thorough study of aesthetic medicine treatments, Natura Bissé has created this serum with its highest concentration of rejuvenating ingredients. Its complex of neuropeptides, firming peptides, growth factors, and hyaluronic acid of four molecular weights works synergistically to transform the appearance of the skin exactly where you need it most: forehead, between-the-brows, eye contour, grooves, and the facial oval.

• Relax: helps soften expression lines caused by ongoing facial contractions.
• Fill: provides volume and juiciness so that wrinkles appear optically cushioned.
• Tighten: helps redensify the skin, fighting sagging and enhancing contours.
• Repair: improves tone, texture, and hydration to reveal a noticeably rejuvenated complexion.

The results perceived in a subjective test in 21 women after 28 days of use confirm its effectiveness: 100% say it reduces wrinkles, 95% feel a filling effect and firmer, more flexible and elastic skin, and 86% perceive an immediate lifting effect.

Next-generation neuropeptides for a more relaxed expression

At the heart of Inhibit High Definition Serum is a powerful combination of neuropeptides: Octamioxyl® and RelaxTripeptyl, a revolutionary octapeptide and a relaxing neuropeptide that work complementarily to help reduce the appearance of lines associated with repetitive gestures.

• Octamioxyl® and RelaxTripeptyl: work on facial micro-contractions, helping lines on the forehead, between-the-brows, or around the eyes appear softer with continued use.

Due to its cosmetic mechanism of action, this serum is perfect as a complement or alternative to procedures such as botulinum toxin (Botox®), extending and enhancing their results from home.

Firming complexes and growth factors for redensified skin

Beyond wrinkles, the face’s structure also evolves over time. To meet this need, Inhibit High Definition Serum includes firming peptides, growth factors, and bioactive ingredients that work on the skin’s firmness and overall quality.

• Matrixyl: restructuring peptide that helps improve firmness and elasticity, providing a visible lifting effect and helping minimize the appearance of wrinkles.
• PDGF (Platelet-Derived Growth Factor): Key growth factor for regenerating the appearance of the skin. Helps transform the face’s appearance by boosting firmness and restoring flexibility.
• BioMimetic Complex: bioidentical active ingredient that reconstitutes 5 anti-aging growth factors, amino acids, and essential nutrients to support the skin’s natural rejuvenation processes.
• Copper peptides and collagen: toning action; helps combat the loss of elasticity, improving firmness and the quality of skin tissue.

Dermafill Complex-III and hyaluronic acid of four molecular weights

The dimension of volume and juiciness is entrusted to a sophisticated multi-layer hydration system that works at different levels of the epidermis to provide plumpness and comfort.

• Dermafill Complex-III: combines hyaluronic acid with next-generation moisturizing agents such as Aquaxyl and niacinamide, for visibly fuller, juicier, and more elastic-looking skin.
• Complex of hyaluronic acid with 4 molecular weights (Hydrolyzed Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer): provides deep, long-lasting hydration, helps fill the look of wrinkles, and improves the skin’s flexibility.

The result is a cushioned effect that smooths the skin’s texture and delivers a feeling of densified, firm, and comfortable skin from the very first application.

Expert sensory texture and application ritual

With a silky, enveloping texture, Inhibit High Definition Serum spreads easily and melts into the skin without leaving a sticky residue. Its finish is elegant and comfortable—perfect for incorporating into both your daytime and nighttime routine, either alone or as a base under the treatment cream.

To enhance its effect, Natura Bissé recommends applying it with the exclusive High Definition Lifting Massage, a facial massage protocol that uses upward sculpting maneuvers to enhance the oval and contours. The gesture then becomes a true “at-home carpet” ritual.

How to use Inhibit High Definition Serum

Use this intensive corrective serum as the central step in your treatment routine, always on clean and toned skin.

• Morning and night: apply daily to the face, neck, and décolleté, avoiding the immediate eye contour area.
• Application technique: place a small amount in the palm, lightly warm it between your hands, then distribute using upward movements, focusing on areas with prominent lines (forehead, between the eyebrows, and nasolabial folds).
• Precision massage: use gentle pressing and soft “pinching” maneuvers on the most visible wrinkles to intensify the plumping effect.
• Complete ritual: next, apply your usual treatment cream; in the morning, don’t forget to finish with a broad-spectrum sunscreen.

If your skin has specific needs—such as pronounced dryness or dark spots—you can combine Inhibit High Definition Serum with other serums from Natura Bissé, applying them in layers or in a targeted way according to the advice of your trusted professional.

Complete list of ingredients

The formulation of Inhibit High Definition Serum has been developed in accordance with high-end cosmetic standards: gluten-free, alcohol-free, and with carefully selected ingredients to provide excellent sensory characteristics and high anti-aging efficacy. The full composition is detailed below for absolute transparency:

Formula (INCI):
Water (Aqua), C12-20 Acid PEG-8 Ester, Niacinamide, Propanediol, Betaine, Pentaerythrityl Tetracaprylate/Tetracaprate, Glycerin, Glyceryl Stearate, Dimethicone, Panthenol, Butyrospermum Parkii (Shea) Butter, Amaranthus Caudatus Seed Extract, Hydrolyzed Collagen, Mangifera Indica (Mango) Seed Butter, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Anhydroxylitol, Arginine, Avena Sativa (Oat) Kernel Extract, C10-30 Cholesterol/Lanosterol Esters, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Glucose, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Phospholipids, Polyglyceryl-10 Stearate, Pseudoalteromonas Ferment Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Saccharomyces Cerevisiae Extract, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Lactate, Tocopherol, Tripeptide-1, Tripeptide-10 Citrulline, Xylitol, Xylitylglucoside, Titanium Dioxide (CI 77891), Butylene Glycol, Caprylyl Glycol, Decylene Glycol, Ethylhexylglycerin, Hexanediol, Pentylene Glycol, Dimethiconol, Helianthus Annuus (Sunflower) Seed Oil, Hydrogenated Polydecene, Carbomer, Cetyl Phosphate, Lecithin, Polysorbate 20, Sodium Acrylates Copolymer, Xanthan Gum, Benzotriazolyl Dodecyl P-Cresol, Disodium EDTA, Mica, Octadecyl Di-T-Butyl-4-Hydroxyhydrocinnamate, Silica, Phenoxyethanol, Sodium Benzoate, Fragrance (Parfum), Benzyl Benzoate, Beta-Caryophyllene, Camphor, Cananga Odorata Oil/Extract, Cinnamyl Alcohol, Citral, Citronellol, Citrus Aurantium Peel Oil, Citrus Limon (Lemon) Peel Oil, Geraniol, Geranyl Acetate, Hexamethylindanopyran, Juniperus Virginiana Oil, Lavandula Oil/Extract, Limonene, Linalool, Linalyl Acetate, Pinene, Terpineol, Vanillin, Caramel, Yellow 5 (CI 19140).

Please note that the ingredient list may be updated over time. Always check the physical packaging of the product to verify the exact composition corresponding to your batch.