Gel Cream Clear Skin R is a cutting-edge nighttime depigmenting treatment that combines science, biotechnology, and sensoriality to transform skin with dark spots, dull tone, or residual marks. Its intelligent formula works globally on hyperpigmentation and signs of aging, smoothing texture, improving firmness, and restoring homogeneous, sophisticated radiance to the face, décolleté, and hands.
Who is it intended for?
This gel cream has been developed for those seeking an intensive, effective, and elegant overnight routine—capable of treating both dark spots and aging at once without sacrificing comfort:
- Skin with dark spots (sun lentigines, melasma, post-inflammatory hyperpigmentation).
- Skin with uneven tone, lack of luminosity, and irregular texture.
- People who want a nighttime treatment that combines targeted depigmenting action and global anti-aging (wrinkles, firmness, pores).
- Skin that has undergone intense sun exposure, medical or dermatological treatments and wants to prevent or correct hyperpigmentation.
- Not suitable during pregnancy or breastfeeding due to its content of pure retinol.
Skin results and benefits
Clear Skin R has been formulated to provide multi-target action on spots and the skin’s overall quality, with visible and progressive results:
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Visibly reduces spots of different origins (sun-related, hormonal, post-inflammatory) and helps prevent their return.
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Unifies the tone and delivers elegant luminosity, without a dull effect or a sallow appearance.
- Works as global anti-aging treatment: improves firmness, smooths wrinkles and expression lines, and refines the appearance of pores.
- The skin feels smoother, clearer, and more even, with a refined skin texture.
- Its gel-cream texture envelops the skin in a comfortable veil, ideal as the last step of the nighttime ritual for all skin types.
Advanced depigmenting technology and dermatological inspiration
The Gel Cream Clear Skin R formula is inspired by the well-known “Kligman’s Tríad” dermatological approach, adapting its philosophy to a contemporary cosmetic perspective: effective, yet respectful of the skin barrier. To do this, it combines different types of actives that target the main pathways involved in the formation of spots and skin aging:
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Tyrosinase inhibitors that reduce melanin synthesis.
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Anti-inflammatory actives that modulate the response triggered by hyperpigmentation.
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Keratolytic actives that accelerate cell renewal to eliminate pigmented cells.
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Powerful antioxidants and biotechnological actives that protect against oxidative stress and radiation.
The result is a multi-purpose treatment that addresses spots from their source, improves texture, and strengthens the skin’s overall quality—minimizing the risk of irritation associated with traditional depigmenting protocols.
Key actives and the science behind the formula
4-Butylresorcinol 0.5% – Next-generation depigmenting
4-Butylresorcinol is one of the most advanced tyrosinase inhibitors in depigmenting cosmetics. It acts directly on the enzyme responsible for melanin synthesis, helping to slow down pigment overproduction.
- Helps to reduce the intensity of dark spots and brighten the overall tone.
- Helps prevent the appearance of new hyperpigmentations.
- Provides a more even and luminous tone.
- Offers high tolerance compared with classic depigmenting agents such as hydroquinone.
Pure Retinol 0.2% – Anti-aging gold standard
Pure retinol at 0.2% is a vitamin A derivative considered the reference standard in anti-aging treatments. It works at the cellular level to accelerate epidermal renewal and stimulate skin repair mechanisms.
- Softens wrinkles and expression lines by stimulating collagen and elastin synthesis.
- Promotes a more even tone and helps blur dark spots and pigment irregularities.
- Refines texture and improves the appearance of pores.
- Regulates excess sebum, making it an ally for combination skin or skin prone to acne.
Niacinamide 5% – Multi-task action on tone, barrier and sebum
Niacinamide (vitamin B3) at 5% provides comprehensive action on skin quality, combining a depigmenting, soothing, and barrier-strengthening effect.
- Helps reduce dark spots and tone irregularities.
- Calms redness and irritation by modulating inflammation.
- Regulates excess oil and improves the look of pores.
- Strengthens the skin barrier, increasing hydration and elasticity.
- Provides antioxidant protection against the signs of aging.
Tranexamic Acid 3% – Specialist in melasma and post-inflammatory hyperpigmentation
Tranexamic acid is a key active ingredient for treating complex dark spots, especially melasma and post-inflammatory marks caused by acne or other irritating processes.
- Reduces the intensity of spots and melasma.
- Unifies the tone and helps restore luminosity.
- Modulates the inflammatory pathways that activate melanocytes.
- Helps prevent the appearance of new hyperpigmentations associated with inflammatory processes.
N-acetylglucosamine 2% – Hydration, regeneration and depigmenting support
N-acetylglucosamine is a glucose derivative that skin uses as a precursor to hyaluronic acid. Its presence in the formula enhances both hydration and spot-fighting action.
- Stimulates the natural production of hyaluronic acid, improving hydration and elasticity.
- Helps reduce spots and even out the tone, especially when combined with niacinamide.
- Promotes regeneration and healing.
- Strengthens the barrier function, improving resistance against external aggressors.
Licorice root extract (glabridin) – Soothing depigmenting
Licorice extract, rich in glabridin, provides natural depigmenting action paired with a pronounced soothing and antioxidant effect.
- Lightens spots and helps create a more even tone.
- Calms the skin and reduces redness and irritation.
- Protects against oxidative damage.
- Especially interesting for sensitive or reactive skin with a tendency toward hyperpigmentation.
Pomegranate stem cells (Punica granatum) – Green biotechnology for selective action
Pomegranate stem cells, obtained through green biotechnology, concentrate polyphenols such as ellagic acid and gallic acid, with a powerful selective antioxidant and skin-lightening action.
- Protect against oxidative stress and UV radiation.
- Provide smart skin-lightening action, working more intensely on the hyperpigmented area.
- Help improve firmness, elasticity, and luminosity.
- Help preserve the evenness of skin tone and skin vitality.
Vitamin E – Antioxidant shield
Vitamin E strengthens the skin’s defense against free radicals and environmental aggressors.
- Neutralizes free radicals that speed up skin aging.
- Reinforces the skin barrier and helps maintain hydration.
- Soothes irritation and helps reduce redness.
- Complements and enhances the action of other antioxidants present in your routine.
Centella asiatica extract – Repair and comfort
Centella asiatica is known for its ability to stimulate collagen synthesis and accelerate skin repair processes.
- Promotes collagen production, improving firmness and elasticity.
- Accelerates the repair of skin subjected to intensive treatments.
- Calms redness, irritations, and feelings of discomfort.
- Provides additional antioxidant action, protecting against aging.
Sensorial experience and texture
Clear Skin R has a lightweight yet enveloping cream-gel texture, which melts upon contact with the skin and spreads easily, allowing both localized application on spots and use across the entire face, neck, décolleté, and hands. Its balanced finish delivers comfort without a heavy feel, integrating elegantly into any nighttime ritual of advanced care.
How to use and recommended ritual
To maximize results and maintain skin balance, it is recommended to integrate Clear Skin R Cream Gel into a progressive nighttime routine:
- Apply exclusively at night to clean, completely dry skin.
- Dispense a small amount and spread it over the face, neck, décolleté, and/or hands, avoiding the eye contour. It can also be applied locally to specific spots.
- Because it contains 0.2% pure retinol, start using it at a frequency of 1–2 nights per week and gradually increase according to skin tolerance.
- For sensitive skin, alternate nights or apply, about 20 minutes after, a repairing serum or cream (for example, Skin Factor-type formulas for normal/dry skin or Blue Balance for combination/oily skin) to strengthen the barrier and minimize the risk of irritation.
- Once your skin has adapted, it can be used more frequently, always following the guidance on individual tolerance.
Recommended synergies in your routine
Clear Skin R fully unfolds its potential when incorporated into a structured nighttime routine, supported by specific daytime care:
- At night, as a main treatment step after cleansing and the eye contour, followed by a cream if the skin is dry (leaving about 15 minutes between layers).
- Once a week, its renewing action can be enhanced by combining it with a glycolic-type exfoliating serum (such as Glicolmix) in a controlled routine, to speed up the removal of pigmented cells.
- In the morning, complete your routine with antioxidant serums (for example, formulas with vitamin C or niacinamide) and with the Clear Azelaic Cream Gel to reinforce its anti-spot and anti-imperfection action.
- Daily and generous use of SPF50+ photoprotection is essential to prevent spots from returning and to protect the results of the nighttime treatment.
Complete list of ingredients (INCI)
INCI: AQUA, CAPRYLIC/CAPRIC TRIGLYCERIDE, PENTYLENE GLYCOL, NIACINAMIDE, GLYCERIN, TRANEXAMIC ACID, CETYL ALCOHOL, ACETYL GLUCOSAMINE, PROPYLENE GLYCOL, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, CETEARYL ALCOHOL, TOCOPHERYL ACETATE, PUNICA GRANATUM SEED CELL CULTURE LYSATE, CENTELLA ASIATICA EXTRACT, GLYCYRRHIZA GLABRA ROOT EXTRACT, 4-BUTYLRESORCINOL, BISABOLOL, RETINOL, PHOSPHOLIPIDS, GLYCERYL CAPRYLATE, CITRIC ACID, CETEARYL GLUCOSIDE, XANTHAN GUM, BIOSACCHARIDE GUM-1, MALTODEXTRIN, SODIUM LEVULINATE, POTASSIUM SORBATE, SODIUM BENZOATE, SODIUM ANISATE, FARNESOL, PARFUM.
