Rediscover the youthful potential of your skin with Epigen Advanced+ de DR. GRANDEL, a high-precision treatment ampoule that applies epigenetics advances to cosmetics. Its light, silky texture instantly melts into the skin, delivering a luxurious feel and leaving the face smoother, firmer, and visibly rejuvenated from the first applications.
Global correction of the signs of aging
Epigen Advanced+ was designed as a true global anti-aging treatment, created to address the main signs of skin aging:
- Smooths and evens out skin texture, reducing fine lines and marked wrinkles, even expression lines.
- Helps to reaffirm the facial oval and improve the sensation of density and elasticity.
- Helps slow the breakdown of collagen and stimulates its synthesis for skin that is more resistant and flexible.
- Fades the appearance of age spots and signs of photoaging, revealing a more even, luminous tone.
- Enhances the skin’s ability to regenerate, promoting a rested and rejuvenated look.
Epigenetic technology: advanced science in the service of skin
Epigenetics studies how external factors can modulate gene activity without altering their DNA. Inspired by this scientific field, DR. GRANDEL has developed a formula that supports the skin’s biological processes and backs its natural functions of regeneration and repair.
In Epigen Advanced+, an expert combination of next-generation actives works in synergy to:
- Protect the skin from the effects of environmental stress and UV radiation, slowing the appearance of visible signs of aging.
- Boost self-skin-regeneration mechanisms for stronger, more resilient skin.
- Improve the overall quality of the skin surface: smoother, more even, more luminous.
High-performance active complex
The Epigen Advanced+ Ampoule formula integrates reference actives in scientific cosmetics, carefully balanced to maximize results with excellent tolerability:
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Retin Royal (Hydroxypinacolone Retinoate): a new-generation retinoic acid ester, more active and bio-available than conventional retinol, that stimulates cell renewal, corrects lines and wrinkles, improves tone uniformity, and contributes to a distinctly more youthful appearance.
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Pro Kollagen Peptide (Acetyl Hexapeptide‑1): advanced peptide that helps smooth the skin’s relief and reduce the number and depth of wrinkles, including expression lines. Reduces wear on collagen fibers and stimulates their synthesis, strengthening elasticity.
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Sunflower sprout extract (Helianthus Annuus Sprout Extract): epigenetic active that provides a global approach to photoaging. Helps counteract damage caused by UV radiation, softens the appearance of age spots, and improves skin texture and homogeneity.
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Squalane: a high-affinity lipid with the skin’s own lipids, providing light nourishment, protection, and a silky feel without feeling heavy. Promotes a velvety, comfortable touch.
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Glycerin and Pentylene Glycol: humectants that help maintain hydration in the surface layers of the epidermis, preserving the skin’s softness and flexibility.
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Vitamin E (Tocopherol): an antioxidant that helps neutralize free radicals and reinforces the skin’s defenses against daily oxidative stress.
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Blend of citrus essential oils and juniper wood (Citrus Limon, Citrus Aurantium, Juniperus Virginiana Oil): envelops the skin in a sophisticated aromatic veil, providing a subtle sensation of freshness and well-being.
Application ritual – High-precision intensive treatment
Epigen Advanced+ Ampoules are designed as a professional concentrate to integrate into advanced skincare routines:
- Always use on perfectly cleansed skin of the face, neck, and décolletage.
- Shake the ampoule well before opening it.
- Let the liquid descend from the top using gentle taps.
- Place the marking point facing upward and, with the help of an ampoule opener device, break the top in the opposite direction from the point for added safety.
- Pour the contents little by little into the palm of your hand, avoiding direct contact between the ampoule rim and the skin.
- Apply the concentrate with the fingertips using soft presses and light touches to the face, neck, and décolletage, dedicating a few minutes to complete absorption.
- Finish with your usual treatment cream DR. GRANDEL to seal the concentrate and enhance its effects.
It can be used as a spot treatment for special occasions or as a intensive course for 1–4 weeks, applying the ampoule 2–3 times per week depending on the skin’s needs and the desired level of intensity.
Sensory experience and results
Its light, elegantly satin texture spreads smoothly and absorbs quickly, leaving an immediate sensation of refined comfort. With regular use, the skin feels smoother, firmer, and more re-densified; the tone looks more even, and the features take on a rested, rejuvenated appearance. Epigen Advanced+ thus becomes the perfect ally for those seeking a high-performance anti-aging treatment inspired by the most advanced science.
Ingredients (INCI)
Aqua (Water), Neopentyl Glycol Diheptanoate, C12-15 Alkyl Benzoate, Diisopropyl Adipate, Glycerin, Pentylene Glycol, Propylheptyl Caprylate, Maltodextrin, Squalane, Polyglyceryl-6 Laurate, Lauryl Glucoside, Myristyl Glucoside, Acacia Senegal Gum, Xanthan Gum, Sodium Stearoyl Glutamate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Tocopherol, Caprylhydroxamic Acid, Helianthus Annuus (Sunflower) Sprout Extract, Acetyl Hexapeptide-1, Tetramethyl Acetyloctahydronaphthalenes, Limonene, Citrus Limon (Lemon) Peel Oil, Linalool, Linalyl Acetate, Alpha-Isomethyl Ionone, Hydroxycitronellal, Benzyl Salicylate, Juniperus Virginiana Oil, Pinene, Citrus Aurantium Peel Oil, Hexyl Cinnamal, Geraniol, Parfum (Fragrance)
Due to possible variations between batches, the list of ingredients on the packaging is always the definitive reference.
Usage and safety recommendations
Epigen Advanced+ Ampoules are a topical concentrate for exclusively external use. They should never be opened with bare hands and the direct contact of the area of breakage with the skin should not be allowed. Avoid the eye contour and keep the product out of the reach of children. Each ampoule is intended for immediate use after opening, to preserve the stability and effectiveness of the active ingredients.