Collagen NAD+ Serum

Discover a next-generation facial treatment that goes beyond conventional collagen. The SEGLE Biotech Collagen NAD+ Serum has been formulated to restore the skin’s energy, firmness, and radiance, acting on the deep mechanisms of cellular longevity while intensely strengthening the barrier function. Ideal for dull, tired skin or skin with loss of density, it provides a sophisticated sensory experience and visible results of overall rejuvenation.

Indications and skin type

• Dull, tired skin with loss of luminosity and comfort.
• Face, neck, and décolleté with sagging or loss of firmness.
• Skin with visible wrinkles and uneven texture.
• Need for deep hydration and reinforcement of the skin barrier.
• People seeking an advanced anti-aging approach based on cellular energy (NAD+ and sirtuins).

Key benefits

• Firmness and re-densifying effect: activates collagen and elastin production, improving skin elasticity and density.
• Softens wrinkles and expression lines, reducing their depth and providing a smoother, more even appearance.
• Restores healthy radiance to the skin, a more even tone, and a visibly more youthful look.
• Deep, long-lasting hydration, with a juicy, comfortable, and flexible-feeling skin.
• Strengthens the skin barrier, improving resistance against external aggressors and dehydration.
• Reactivates cellular energy by increasing NAD+ levels and the activity of sirtuin proteins, helping to slow visible aging.

Anti-aging technology: beyond collagen

Skin aging is not caused solely by collagen loss. The Collagen NAD+ formula tackles the origin of aging through a biotech axis that acts on NAD+, sirtuins, mitochondria, and telomeres. In this way, it supports the defense, repair, and functional longevity of skin cells, achieving a firmer, brighter, hydrated, and structurally youthful complexion.

Main actives and action on the skin

Collagen peptides, elastin, and hyaluronic acid from egg shell membrane (Rejuvecoll®)

Patent-pending ingredient obtained from the natural membrane that lines the inside of the eggshell, a unique and sustainable source of type I, V, and X collagen, elastin, hyaluronic acid, chondroitin sulfate, glucosamine, and cysteine.

• Stimulates fibroblasts to synthesize new collagen, elastin, and hyaluronic acid.
• Significantly improves the firmness, elasticity, and density of the dermis.
• Fights sagging and softens visible signs of aging (wrinkles and fine lines).
• Provides antioxidant and anti-inflammatory action, reducing oxidative stress and cellular damage.
• Promotes skin regeneration and repair, improving hydration, flexibility, and recovery ability.

Structural amino acids from collagen of the algae Haematococcus pluvialis

A complex of amino acids that mimic the structural components of natural skin collagen, obtained from the microalgae Haematococcus pluvialis. They act as essential “raw material” to rebuild the dermal architecture.

• They stimulate the synthesis of collagen and elastin, improving firmness and skin support.
• They redensify the skin, making it feel more “plump,” smooth, and juicy.
• Smooth wrinkles and refine the texture, providing a more even finish.
• Improve the skin’s ability to reflect light, increasing the face’s overall brightness.

NAD+ booster complex – repair enzymes of Chlorella vulgaris

A marine biotechnological complex derived from the microalga Chlorella vulgaris, designed to boost cellular energy and enhance the skin’s natural repair processes.

• Increases NAD⁺ levels, a key molecule for energy metabolism and cellular vitality.
• Promotes the repair of DNA damaged by oxidative stress and the passage of time.
• Strengthens the skin’s resistance to intrinsic and extrinsic cutaneous aging.
• Visibly improves the look of tired skin: firmer, more even, and radiant.

Niacinamide (Vitamin B3)

A high-tolerance, multifunction active suitable for all skin types, including sensitive skin, that works globally on skin quality.

• Helps reduce the appearance of dark spots and tone irregularities, unifying skin color.
• Soothes redness and irritation, improving daily comfort.
• Regulates excess sebum and improves the appearance of enlarged pores.
• Strengthens the skin barrier by stimulating ceramide synthesis, increasing hydration and elasticity.
• Provides antioxidant protection against free radicals and premature aging.

Biomimetic ceramides, cholesterol, and skin lipids

Ceramides account for around 50% of skin lipids and act as the “cement” that keeps cells together. Their combination with cholesterol and other key lipids deeply restores the skin barrier.

• Repairs and strengthens the hydro-lipid barrier, improving the skin’s protective function.
• Reduces dryness and the feeling of tightness, providing immediate and long-lasting comfort.
• Increases the elasticity and flexibility of the skin surface.
• Protects against external aggressors such as cold, pollution, and irritant agents.

Low molecular weight hyaluronic acid

A key active for intensive hydration, capable of retaining a large amount of water in the skin.

• Provides deep and long-lasting hydration, keeping skin plump and soft.
• Exerts a filling effect, softening wrinkles and expression lines from within.
• Improves skin elasticity and resilience.
• Strengthens the natural barrier and supports repair and regeneration processes.

How to use

• Apply in the morning and at night to clean, dry skin of the face, neck, and décolleté.
• Dispense 3 to 4 drops into the palm of your hand or directly onto the skin.
• Spread with gentle patting or pressing, avoiding excessive dragging, until fully absorbed.
• Next, apply your usual treatment cream and sunscreen during the day.

For an even more complete pro-firming routine, it can be combined with the DMAE Lift 10 serum. In that case, it is recommended to apply the DMAE Lift 10 serum first (with a more watery texture) and then the Collagen NAD+ Serum.

Expected results (according to efficacy studies)

• Significant improvement in skin elasticity and firmness.
• Increased hydration and skin comfort.
• Boost in brightness and a revitalized appearance of the face.
• Stimulation of NAD⁺ production, key for energy and cellular longevity.

Full list of ingredients (INCI)

AQUA, ISONONYL ISONONANOATE, BUTYLENE GLYCOL, GLYCERIN, NIACINAMIDE, CICHORIUM INTYBUS ROOT OLIGOSACCHARIDES, DIMETHICONE, HYDROGENATED POLYDECENE, CAPRYLIC/CAPRIC TRIGLYCERIDE, POLYSORBATE 20, STEARYL HEPTANOATE, BUTYLENE GLYCOL DICAPRYLATE/DICAPRATE, HYDROLYZED EGG SHELL MEMBRANE, COLLAGEN AMINO ACIDS, GLYCYRRHIZA GLABRA ROOT EXTRACT, CERAMIDE NP, CERAMIDE AP, CHOLESTEROL, GLYCOSPHINGOLIPIDS, LECITHIN, HYDROGENATED LECITHIN, TOCOPHERYL ACETATE, SODIUM HYALURONATE, TETRAACETYLPHYTOSPHINGOSINE, HAEMATOCOCCUS PLUVIALIS EXTRACT, SPHINGOMONAS FERMENT EXTRACT, CHLORELLA VULGARIS EXTRACT, SODIUM PHYTATE, SUCCINOGLYCAN, CAESALPINIA SPINOSA GUM, ACACIA SENEGAL GUM, XANTHAN GUM, SODIUM LEVULINATE, GLUCONOLACTONE, CAPRYLYL GLYCOL, PROPANEDIOL, PROPYLENE GLYCOL, CITRIC ACID, CETEARYL ALCOHOL, GLYCERYL STEARATE, STEARIC ACID, SODIUM BENZOATE, PENTYLENE GLYCOL, POTASSIUM SORBATE, CALCIUM GLUCONATE, ISOEUGENYL ACETATE, ACETYL CEDRENE, DIMETHYL PHENETHYL ACETATE, 1,2-HEXANEDIOL, VANILLIN, SODIUM BENZOATE, HEXAMETHYLINDANOPYRAN, TETRAMETHYL ACETYLOCTAHYDRONAPHTHALENES, PARFUM.